Foundations of Computational and Systems Biology

Syllabus

1. Week 1

   Sequence alignment — pairwise

2. Week 2

   Multiple sequence alignment; profile HMMs

3. Week 3

   BLAST and database search

4. Week 4

   Gene prediction; splice sites

5. Week 5

   Phylogenetic inference

6. Week 6

   RNA structure prediction

7. Week 7

   Protein structure prediction

8. Week 8

   Microarrays and RNA-seq analysis

9. Week 9

   Regulatory networks; ChIP-seq

10. Week 10

    Systems modelling of cellular processes

11. Week 11

    GWAS and population genomics

12. Week 12

    Single-cell genomics; cancer genomics